Devel., Dynamics and Pathology of Neuronal Networks [Prog. by J. van Pelt

Devel., Dynamics and Pathology of Neuronal Networks [Prog. by J. van Pelt

By J. van Pelt

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From Washington University in the Neural Sciences and was a postdoctoral fellow at the Salk Institute. Presently, he is a professor in the Molecular Neurobiology Laboratory, studying genes that guide brain development in the growing embryo. He focuses on the genes that orchestrate cell identity and arrange connections in the cortex, the part of the brain that controls perception, reasoning and voluntary actions. O’Leary’s lab identified the first genes that ‘‘tell’’ cortex cells their function. For example, the gene Emx-2 can switch cells that normally make up motor cortex into visual cortex.

Despite their small size, dendritic spines also contain molecular machinery for many other functions, including local control of membrane trafficking, protein synthesis, post-translational processing, and protein degradation. , 2002). ER is thought to contribute not only to trafficking of membrane proteins but also to regulation of calcium dynamics within the spines. , 1992; Sorra and Harris, 2000). In addition, many dendrites have polyribosomes just beneath the spine neck, and there is growing evidence that protein synthesis and protein degradation can occur locally within spines (Jiang and Schuman, 2002; Ehlers, 2003; Steward and Schuman, 2003).

Thesis on the neuroanatomy of bony and cartilaginous fishes. , head of the department) at the ‘‘Senckenbergisch-Neurologisches Institut’’ of the famous neurologist and comparative neuroanatomist Prof. Ludwig Edinger in Frankfurt am Main, Germany. Meanwhile, at the meeting of the International Association of Academies held in Paris in 1901, the anatomist Dr. Wilhelm His proposed that research on the nervous system should be placed on an international footing. Thus, on 5 June 1903, at Burlington House in London, the former headquarters of the Royal Society, the ‘‘Central Commission for Brain Research’’ was constituted.

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