An Atlas of Induced Sputum: An Aid for Research and by Ratko. Djukanovic, Peter Sterk

An Atlas of Induced Sputum: An Aid for Research and by Ratko. Djukanovic, Peter Sterk

By Ratko. Djukanovic, Peter Sterk

Containing greater than a hundred and fifty photos of the best quality, An Atlas of triggered Sputum: An reduction for learn and analysis is the 1st complete medical consultant at the software of this diagnostic strategy to non-infectious inflammatory illnesses. The booklet comprises contributions from major specialists during this swiftly starting to be box who have been individuals within the activity strength on caused sputum backed by means of the ecu breathing Society and chaired via the editors of this Atlas, Drs. Djukanovic and Sterk. proposing various graphs and illustrations, the atlas expertly describes concepts and systems and offers transparent innovations for sputum induction and research in line with the ecu respiration Society activity strength file. A diagnostic reference for pulmonologists, the atlas does double responsibility as an instructive textual content for citizens and physicians in education.

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Additional resources for An Atlas of Induced Sputum: An Aid for Research and Diagnosis (Encyclopedia of Visual Medicine Series)

Sample text

Eosinophilic bronchitis can also be present in atopic cough without asthma, allergic rhinitis, and in a proportion of patients with chronic obstructive pulmonary disease (COPD). It is also important to note that symptoms and physiological abnormalities of asthma can be present without evidence of eosinophilic bronchitis and this may be associated with sputum neutrophilia. 9). Macrophages are the predominant cell type in healthy subjects and, in comparison with granulocytes, they have a longer life span and thus reside in the airways much longer.

THE COMPOSITION OF SPUTUM Sputum is a complex mixture of inflammatory cells, debris, exfoliated epithelial cells, water, ions; proteins and lipids, all held together within a mucus gel. The physical properties of mucus are determined by the presence of mucus glycoproteins (mucins) which consist of large peptide molecules forming a backbone upon which are attached numerous oligosaccharide sidechains. The large number of hydrophobic and hydrophilic sites present in these molecules allow multiple low-affinity bonds to occur with virtually any substance, accounting for the marked ‘stickiness’ of mucus.

SD, standard deviation. Adapted with permission from Efthimiadis A, Pizzichini MM, Pizzichini E, et al. Induced sputum cell and fluid-phase indices of inflammation: comparison of treatment with dtt vs. PBS. 14 Concentrations of eosinophil cationic protein (ECP), eosinophil Analysis of soluble mediators in the sputum fluid phase 55 protein X (EPX), eosinophil peroxidase (EPO), and myeloperoxidase (MPO) in induced sputum that was homogenized by different methonds (means ± standard deviation). It can be seen that the measurement of EPO and MPO was markedly reduced in sputum after dithiothreitol (DTT) was added to the ultrasonically homogenized (U) sample.

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